Glycogen Synthase antibody (pSer9)

Catalog No. ABIN5688910

The Rabbit Polyclonal anti-Glycogen Synthase antibody has been validated for WB. It is suitable to detect Glycogen Synthase in samples from Human, Mouse, Rat, Chicken, Cow, Dog, Xenopus laevis and Zebrafish (Danio rerio).

Quick Overview for Glycogen Synthase antibody (pSer9) (ABIN5688910)

Target: Glycogen Synthase (GYS)

Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glycogen Synthase Antibody

Binding Specificity: pSer9

Purification: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3b.

Application Details

Application Notes: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, chicken, bovine, canine, non-human primate, Zebra fish and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Glycogen synthase antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for Glycogen Synthase

Target: Glycogen Synthase (GYS)

Alternative Name: Glycogen synthase

Background: Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, 2 isoforms have been identified: GSK3alpha and GSK3beta. Specifically, GSK3beta has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways (Papkoff and Aikawa 1998). It has been suggested that Ser9 phosphorylation underlies the inhibition of GSK3beta by insulin (Sutherland et al., 1993).

Molecular Weight: 46 kDa

Gene ID: 84027

UniProt: P18266