Glycogen Synthase antibody

Catalog No. ABIN6943562

Product Details anti-Glycogen Synthase Antibody

Target: Glycogen Synthase (GYS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glycogen Synthase antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant human Glycogen synthase between 700 to 800 amino acids

Clone: 1A8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Glycogen Synthase

Target: Glycogen Synthase (GYS)

Alternative Name: Glycogen synthase (GYS Products)

Synonyms: CG6940 antibody, Dmel\\CG6904 antibody, anon-WO0118547.108 antibody, glycogen synthase antibody, Glycogen synthase antibody, starch synthase antibody, glgA antibody, GlyS antibody, glgA-2 antibody, glgA-1 antibody, EAMY_RS33325 antibody, Hipma_0956 antibody, Tresu_1353 antibody, Spico_0935 antibody, Trebr_1511 antibody, Mahau_1987 antibody

Background:

Synonyms: Glycogen [starch] synthase, muscle, GYS1

Background: Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Gene ID: 2997

UniProt: P13807