Synaptotagmin antibody (Ser309)

Catalog No. ABIN5688918

This Rabbit Polyclonal antibody specifically detects Synaptotagmin in WB and IHC. It exhibits reactivity toward Rat, Mouse and Human.

Quick Overview for Synaptotagmin antibody (Ser309) (ABIN5688918)

Target: Synaptotagmin (SYT)

Reactivity: Rat, Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Synaptotagmin Antibody

Binding Specificity: Ser309

Specificity: Synaptotagmin antibody is specific for Mr 60 - 62k synaptotagmin phosphorylated at Ser309.

Purification: Affinity Purified

Immunogen: Synaptotagmin (Ser309) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin.

Application Details

Application Notes: Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. Human, mouse, and rat have 100 % amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

Target Details for Synaptotagmin

Target: Synaptotagmin (SYT)

Alternative Name: Synaptotagmin

Background: Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis. Moreover recent studies indicate that the protein also plays a key role in endocytosis. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission.

Molecular Weight: 60/62 kDa

Gene ID: 25716

UniProt: P21707