ITGA4 antibody (AA 1024-1028)

Catalog No. ABIN5689252

The Rabbit Polyclonal anti-ITGA4 antibody has been validated for WB. It is suitable to detect ITGA4 in samples from Human.

Quick Overview for ITGA4 antibody (AA 1024-1028) (ABIN5689252)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITGA4 Antibody

Binding Specificity: AA 1024-1028

Specificity: This antibody detects endogenous level of total LPAM-1(Integrin α,4, CD49d) protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: LPAM-1 (Integrin a4, CD49d) antibody was raised against a peptide sequence around aa.1024~1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin α,4, CD49d).

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: LPAM 1

Background: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Molecular Weight: 70, 140, 180 kDa

Gene ID: 3676

NCBI Accession: NP_000876

UniProt: P13612

Pathways: Integrin Complex