HSD17B10 antibody (AA 253-257)

Catalog No. ABIN5689461

This Rabbit Polyclonal antibody specifically detects HSD17B10 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HSD17B10 antibody (AA 253-257) (ABIN5689461)

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSD17B10 Antibody

Binding Specificity: AA 253-257

Specificity: This antibody detects endogenous level of total ERAB protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: ERAB antibody was raised against a peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Alternative Name: ERAB

Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Molecular Weight: 27 kDa

Gene ID: 3028

NCBI Accession: NP_004484

UniProt: Q99714