SYK antibody (AA 321-325)

Catalog No. ABIN5689584

This Rabbit Polyclonal antibody specifically detects SYK in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SYK antibody (AA 321-325) (ABIN5689584)

Target: SYK (Spleen tyrosine Kinase (SYK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SYK Antibody

Binding Specificity: AA 321-325

Specificity: This antibody detects endogenous level of total syk protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: syk (Ab-323) antibody was raised against a peptide sequence around aa. 321~325 (N-P-Y-E-P) derived from Human syk.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Alternative Name: syk

Background: Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C γ,dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion

Molecular Weight: 72 kDa

Gene ID: 6850

NCBI Accession: NP_001128524

UniProt: P43405

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling