RPS6KA3 antibody (pThr348)

Catalog No. ABIN5689711

The Rabbit Polyclonal anti-RPS6KA3 antibody has been validated for WB, IHC and IF. It is suitable to detect RPS6KA3 in samples from Human, Mouse and Rat.

Quick Overview for RPS6KA3 antibody (pThr348) (ABIN5689711)

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RPS6KA3 Antibody

Binding Specificity: pThr348

Specificity: This antibody detects endogenous level of p90RSK only when phosphorylated at threonine 348.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Immunogen: p90RSK (Phospho-Thr348) antibody was raised against a peptide sequence around phosphorylation site of threonine 348 (S-R-T (p) -P-R) derived from Human p90RSK.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Alternative Name: p90RSK

Background: Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

Molecular Weight: 90 kDa

Gene ID: 6195

NCBI Accession: NP_001006666

UniProt: Q15418

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades