PKC mu antibody (pSer738)

Catalog No. ABIN5689804

The Rabbit Polyclonal anti-PKC mu antibody has been validated for WB and IF. It is suitable to detect PKC mu in samples from Human, Mouse and Rat.

Quick Overview for PKC mu antibody (pSer738) (ABIN5689804)

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC mu antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PKC mu Antibody

Binding Specificity: pSer738

Specificity: This antibody detects endogenous level of PKD/PKCmu only when phosphorylated at serine 738.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Immunogen: PKD/PKCmu (Phospho-Ser738) antibody was raised against a peptide sequence around phosphorylation site of serine 738 (E-K-S (p) -F-R) derived from Human PKD/PKCμ,.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for PKC mu

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Alternative Name: PKD / PKCmu

Background: Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-κ,-B.

Molecular Weight: 115 kDa

Gene ID: 5587

NCBI Accession: NP_002733

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction