C19ORF80 antibody (AA 40-90)

Catalog No. ABIN5689902

This Rabbit Polyclonal antibody specifically detects C19ORF80 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for C19ORF80 antibody (AA 40-90) (ABIN5689902)

Target: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C19ORF80 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C19ORF80 Antibody

Binding Specificity: AA 40-90

Specificity: Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist, this antibody will detect the two largest isoforms.

Purification: Betatrophin antibody is affinity chromatography purified via peptide column.

Immunogen: Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin.

The immunogen is located within amino acids 40 - 90 of Betatrophin.

Isotype: IgG

Application Details

Application Notes: Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Betatrophin antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Betatrophin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for C19ORF80

Target: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Alternative Name: Betatrophin

Background: The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).

Molecular Weight: Predicted: 22 kDa

Observed: 22 kDa

Gene ID: 55908

NCBI Accession: NP_061157

UniProt: Q6UXH0