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KDM1B antibody (AA 80-130)
KDM1B
Reactivity: Human, Mouse
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KDM1B Antibody
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Target
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KDM1B
(Lysine (K)-Specific Demethylase 1B (KDM1B))
Binding Specificity
All epitopes for KDM1B antibodies
AA 80-130
Reactivity
All reactivities for KDM1B antibodies
Human, Mouse
Host
All hosts for KDM1B antibodies
Rabbit
Clonality
All clonalities for KDM1B antibodies
Polyclonal
Conjugate
All conjugates for KDM1B antibodies
This KDM1B antibody is un-conjugated
Application
All applications for KDM1B antibodies
ELISA, Western Blotting (WB)
Specificity
KDM1B antibody is human, mouse and rat reactive. At least two isoforms of KDM1B are known to exist, this KDM1B antibody will detect both isoforms.
Purification
KDM1B antibody is affinity chromatography purified via peptide column.
Immunogen
KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B. The immunogen is located within amino acids 80 - 130 of KDM1B.
Isotype
IgG
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Discover our top product KDM1B Primary Antibody
Alternatives
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Application Details
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Application Notes
KDM1B antibody can be used for detection of KDM1B by Western blot at 0.5 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
KDM1B antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
KDM1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for KDM1B
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Target
KDM1B
(Lysine (K)-Specific Demethylase 1B (KDM1B))
Alternative Name
KDM1B (KDM1B Products )
Synonyms
AOF1 antibody, C6orf193 antibody, LSD2 antibody, bA204B7.3 antibody, dJ298J15.2 antibody, 4632428N09Rik antibody, AI482520 antibody, Aof1 antibody, lysine demethylase 1B antibody, lysine-specific histone demethylase 1B antibody, lysine (K)-specific demethylase 1B antibody, KDM1B antibody, LOC577549 antibody, kdm1b antibody, Kdm1b antibody
Background
Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints, targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).
Molecular Weight
Predicted: 90 kDa Observed: 90 kDa
Gene ID
221656
NCBI Accession
NP_694587
UniProt
Q8NB78
Pathways
Warburg Effect
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