R-Spondin 3 antibody (AA 200-250)

Catalog No. ABIN5690235

This Rabbit Polyclonal antibody specifically detects R-Spondin 3 in WB, ELISA, ICC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for R-Spondin 3 antibody (AA 200-250) (ABIN5690235)

Target: R-Spondin 3 (RSPO3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This R-Spondin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-R-Spondin 3 Antibody

Binding Specificity: AA 200-250

Specificity: RSPO3 antibody is human and mouse reactive. At least three isoforms of RSPO3 are known to exist, this antibody will detect all three.

Purification: RSPO3 antibody is affinity chromatography purified via peptide column.

Immunogen: RSPO3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RSPO3.

The immunogen is located within amino acids 200 - 250 of RSPO3.

Isotype: IgG

Application Details

Application Notes: RSPO3 antibody can be used for detection of RSPO3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RSPO3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RSPO3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for R-Spondin 3

Target: R-Spondin 3 (RSPO3)

Alternative Name: RSPO3

Background: RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis (1,2). RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development (3,4).

Molecular Weight: Predicted: 30 kDa

Observed: 30 kDa

Gene ID: 84870

NCBI Accession: NP_116173

UniProt: Q9BXY4