MEFV antibody (AA 2-29)

Catalog No. ABIN5690335

The Rabbit Polyclonal anti-MEFV antibody has been validated for WB and IP. It is suitable to detect MEFV in samples from Human.

Quick Overview for MEFV antibody (AA 2-29) (ABIN5690335)

Target: MEFV (Mediterranean Fever (MEFV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEFV antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MEFV Antibody

Binding Specificity: AA 2-29

Specificity: Recognizes human pyrin.

Immunogen: Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.

Application Details

Application Notes: Immunoprecipitation: (1:100). Western Blot: (1:500).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for at least 1 year after receipt when stored at -20°C.

Target Details for MEFV

Target: MEFV (Mediterranean Fever (MEFV))

Alternative Name: Pyrin

Background: Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.

Gene ID: 4210

NCBI Accession: NP_000234

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity