IL1RL1 antibody

Catalog No. ABIN5690499

This Rabbit Polyclonal antibody specifically detects IL1RL1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL1RL1 antibody (ABIN5690499)

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL1RL1 Antibody

Specificity: Recognizes soluble human ST2. Detects a band of ~50  kDa by Western blot.

Immunogen: Recombinant human soluble ST2.

Application Details

Application Notes: ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL, suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk, suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Stable for at least 6 months after receipt when stored at -20°C.

Target Details for IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Alternative Name: ST2

Background: The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.

Gene ID: 9173

UniProt: Q01638