DNM2 antibody (AA 177-441)

Catalog No. ABIN5692845

Product Details anti-DNM2 Antibody

Target: DNM2 (Dynamin 2 (DNM2))

Binding Specificity: AA 177-441

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Dynamin 2 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human Dynamin 2 recombinant protein (Position: A177-Q441).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for DNM2

Target: DNM2 (Dynamin 2 (DNM2))

Alternative Name: DNM2 (DNM2 Products)

Synonyms: dynamin-2 antibody, cmtdi1 antibody, cmtdib antibody, dyn2 antibody, dynII antibody, CMT2M antibody, CMTDI1 antibody, CMTDIB antibody, DI-CMTB antibody, DYN2 antibody, DYNII antibody, LCCS5 antibody, Dyn2 antibody, Udnm antibody, DYIIAAB antibody, dnm2 antibody, zgc:114072 antibody, dynamin 2 antibody, dynamin 2 L homeolog antibody, dynamin 2a antibody, dynamin 2-like antibody, DNM2 antibody, dnm2 antibody, dnm2.L antibody, Dnm2 antibody, dnm2a antibody, DNM2L antibody

Background:

Synonyms: Dynamin-2, DNM2, DYN2

Tissue Specificity: Ubiquitously expressed.

Background: Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

UniProt: P50570

Pathways: Toll-Like Receptors Cascades