IL17C antibody (AA 15-194)

Catalog No. ABIN5692881

Product Details anti-IL17C Antibody

Target: IL17C (Interleukin 17C (IL17C))

Binding Specificity: AA 15-194

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for IL17C detection. Tested with WB, ELISA(Cap) in Mouse,Rat.

Immunogen: E. coli-derived mouse IL17C recombinant protein (Position: H15-Q194).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for IL17C

Target: IL17C (Interleukin 17C (IL17C))

Alternative Name: Il17c (IL17C Products)

Synonyms: IL17C antibody, il17-3 antibody, CX2 antibody, IL-17C antibody, IL-21 antibody, interleukin 17C antibody, interleukin 17c antibody, IL17C antibody, il17c antibody, Il17c antibody

Background:

Synonyms: Interleukin-17C, Il-17c, Cytokine CX2, Il17c

Tissue Specificity: Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes.

Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.

UniProt: Q8K4C5

Pathways: Cellular Response to Molecule of Bacterial Origin