IL-33 antibody (AA 102-264)

Catalog No. ABIN5692884

This Rabbit Polyclonal antibody specifically detects IL-33 in WB, ELISA and IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for IL-33 antibody (AA 102-264) (ABIN5692884)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-33 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IL-33 Antibody

Binding Specificity: AA 102-264

Purpose: Anti-IL33 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IL33 Antibody Picoband® (ABIN5692884). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived rat IL33 recombinant protein (Position: A102-M264).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Alves-Filho, J. C., Sonego, F., Souto, F. O., Freitas, A., Verri, W. A., Jr., Auxiliadora-Martins, M., Basile-Filho, A., McKenzie, A. N., Xu, D., Cunha, F. Q., Liew, F. Y. Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection. Nature Med. 16: 708-712, 2010. 2. Cayrol, C., Girard, J.-P. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc. Nat. Acad. Sci. 106: 9021-9026, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Alternative Name: Il33

Background:

Synonyms: Interleukin-33, IL-33, Il33

Background: Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 31-37 kDa

Gene ID: 361749

UniProt: Q66H70

Pathways: Production of Molecular Mediator of Immune Response