MBL2 antibody (AA 39-229)

Catalog No. ABIN5693271

Product Details anti-MBL2 Antibody

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Binding Specificity: AA 39-229

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for MBL2 detection. Tested with WB, ELISA(Cap) in Mouse,Rat.

Immunogen: E. coli-derived mouse MBL2 recombinant protein (Position: L39-D229).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL
ELISA(Cap),1-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: Mbl2 (MBL2 Products)

Synonyms: COLEC1 antibody, HSMBPC antibody, MBL antibody, MBL2D antibody, MBP antibody, MBP-C antibody, MBP1 antibody, MBPD antibody, pMBP-27 antibody, mbl2 antibody, MBL1 antibody, cMBl antibody, collectin antibody, Ab2-001 antibody, Ab2-011 antibody, L-MBP antibody, MBL-C antibody, COLEC2 antibody, mbl antibody, etID42583.2 antibody, fb68b07 antibody, hbl3 antibody, wu:fb68b07 antibody, zgc:109836 antibody, mannose binding lectin 2 antibody, Mannose-binding protein C antibody, mannose-binding lectin (protein C) 2, soluble antibody, mannose-binding lectin (protein C) 2 antibody, mannose-binding lectin family member 3, pseudogene antibody, MBL2 antibody, mbl2 antibody, Mbl2 antibody, MBL3P antibody

Background:

Synonyms: Mannose-binding protein C, MBP-C, Mannan-binding protein, RA-reactive factor P28A subunit, RARF/P28A, Mbl2

Background: MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.

UniProt: P41317

Pathways: Complement System, Positive Regulation of Immune Effector Process