VCAM1 antibody
Quick Overview for VCAM1 antibody (ABIN569520)
Target
See all VCAM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes Human VCAM-1.
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Purification
- Affinity chromatography employing immobilized Human VCAM-1 matrix.
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Immunogen
- Highly purified recombinant Human VCAM-1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS, pH 7.2 without preservatives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Alternative Name
- CD106 / VCAM1
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Background
- CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110) is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular and interfollicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin alphaBeta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in tumor metastasis.Synonyms: INCAM-100, L1CAM, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1
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Gene ID
- 7412
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NCBI Accession
- NP_001069
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UniProt
- P19320
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Pathways
- Carbohydrate Homeostasis
Target
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