CREM antibody

Catalog No. ABIN5697220

This Rabbit Polyclonal antibody specifically detects CREM in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CREM antibody (ABIN5697220)

Target: CREM (CAMP Responsive Element Modulator (CREM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-CREM Antibody

Purpose: CREM antibody

Immunogen: cAMP responsive element modulator

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

rat testis tissue were subjected to SDS PAGE followed by western blot with FNab01970( CREM Antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Alternative Name: CREM

Background:

Synonyms: cAMP-responsive element modulator|Inducible cAMP early repressor (ICER)|CREM

Background: Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation(PubMed:10373550). Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.

Molecular Weight: 38 kDa

Gene ID: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway