NDE1 antibody

Catalog No. ABIN5700144

This anti-NDE1 antibody is a Rabbit Polyclonal antibody detecting NDE1 in WB, IHC, ELISA, IF and IP. Suitable for Human, Mouse and Rat.

Quick Overview for NDE1 antibody (ABIN5700144)

Target: NDE1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-NDE1 Antibody

Purpose: NDE1 antibody

Immunogen: nudE nuclear distribution gene E homolog 1 (A. nidulans)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

A2780 cells were subjected to SDS PAGE followed by western blot with FNab05600(NDE1 antibody) at dilution of 1:1500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background:

Synonyms: Nuclear distribution protein nudE homolog 1 (NudE)|NDE1|NUDE

Background: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 40 kDa

Gene ID: 54820

UniProt: Q9NXR1