GADD45A antibody

Catalog No. ABIN5700895

This Rabbit Polyclonal antibody specifically detects GADD45A in WB, ELISA and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GADD45A antibody (ABIN5700895)

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-GADD45A Antibody

Purpose: GADD45A antibody

Immunogen: growth arrest and DNA-damage-inducible, alpha

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A

Background:

Synonyms: Growth arrest and DNA damage-inducible protein GADD45 alpha|DNA damage-inducible transcript 1 protein (DDIT-1)|GADD45A|DDIT1|GADD45

Background: In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity(By similarity). Might affect PCNA interaction with some CDK(cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

Molecular Weight: 18 kDa or 36 kDa

Gene ID: 1647

UniProt: P24522

Pathways: p53 Signaling, Cell Division Cycle