CCL3 antibody

Catalog No. ABIN5706842

Product Details anti-CCL3 Antibody

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics:

Synonyms: Tonsillar lymphocyte LD78 alpha protein antibody, CCL 3 antibody, Chemokine CC Motif Ligand 3 antibody, G0/G1 switch regulatory protein 19 1 antibody, SIS beta antibody, Small inducible cytokine A3 antibody, rabbit anti-MIP-1 alpha Antibody

Background: C-C motif chemokine 3, CCL3 or (MIP-1a) is a monokine with inflammatory and chemokinetic properties. CCL3 binds to CCR1, CCR4 and CCR5. It is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Gene Name: CCL3

Purification: This antiserum has been heated to 56° C for 30 minutes.  In ELISA formats and other immunoreactive assays, this antibody will recognize recombinant and native human MIP-1a present in body fluids and cell supernatants.  This antiserum has not been evaluated for its ability to stain human MIP-1a in tissue sections, nor for its ability to neutralize human MIP-1a in bioassays, nor for its performance in immunoblot analysis.

Immunogen:

Immunogen: The whole rabbit serum was prepared by repeated immunizations with recombinant human MIP-1a  produced in E.coli.

Immunogen Type: Recombinant Protein

Application Details

Application Notes:

Application Note: This antiserum against Human MIP-1a has been tested for use in ELISA of human MIP-1a found in cell supernatants or in plasma or serum.  Reactivity in other immunoassays is unknown.

Western Blot Dilution: 1:500 - 1:2,000

ELISA Dilution: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 85 mg/mL

Buffer:

Buffer: None

Stabilizer: None

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 12 months

Target Details for CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Alternative Name: MIP-1 alpha (CCL3 Products)

Synonyms: MIP-1alpha antibody, G0S19-1 antibody, LD78ALPHA antibody, MIP-1-alpha antibody, MIP1A antibody, SCYA3 antibody, MIP-1a antibody, Scya3 antibody, AI323804 antibody, LD78alpha antibody, MIP1-(a) antibody, MIP1-alpha antibody, Mip1a antibody, CCL3L1 antibody, CCL3L3 antibody, chemokine (C-C motif) ligand 3 antibody, C-C motif chemokine ligand 3 antibody, CCL3 antibody, Ccl3 antibody

Gene ID: 6348

UniProt: P10147

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy