Melatonin Receptor 1B antibody (C-Term)

Catalog No. ABIN570709

This Goat Polyclonal antibody specifically detects Melatonin Receptor 1B in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Melatonin Receptor 1B antibody (C-Term) (ABIN570709)

Target: Melatonin Receptor 1B (MTNR1B)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-Melatonin Receptor 1B Antibody

Binding Specificity: C-Term

Purpose: MTNR1B

Sequence: QDASKGSHAE GLQSP

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-QDASKGSHAEGLQSP, from the C Terminus of the protein sequence according to NP_005950.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Cerebellum shows membranous staining primarily in Purkinje cells. Recommended concentration, 3-6 μg/mL.

Western Blot: Preliminary experiments gave approx .48 kDa and 37 kDa bands in Human Brain (Cerebellum) lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calc

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Alternative Name: MTNR1B

Background: MTNR1B, melatonin receptor 1B, MEL-1B-R, MT2, melatonin receptor MEL1B, melatonin receptor type 1B

Gene ID: 4544

NCBI Accession: NP_005950