Tyrosinase-Related Protein 1 antibody (TRP1)

Catalog No. ABIN5708051

This Rabbit Monoclonal antibody specifically detects Tyrosinase-Related Protein 1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Tyrosinase-Related Protein 1 antibody (TRP1) (ABIN5708051)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TYRP1-2340R

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Binding Specificity: AA 257-377, TRP1

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: A portion of amino acids 257-377 was used as the immunogen for this recombinant TRP1 antibody.

Isotype: IgG kappa

Application Details

Application Notes: The optimal dilution of the recombinant TRP1 antibody for each application should be determined by the researcher.\. Immunohistochemistry (FFPE) : 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: Tyrosinase-Related Protein-1

Background: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.