Recombinant Tyrosinase-Related Protein 1 antibody

Catalog No. ABIN5708054

This Rabbit Monoclonal antibody specifically detects Tyrosinase-Related Protein 1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Tyrosinase-Related Protein 1 antibody (ABIN5708054)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TYRP1-1564R

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Purpose: Recombinant TYRP1 Antibody / Tyrosinase Related Protein 1 / TRP1

Purification: Protein A affinity chromatography

Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: TYRP1

Background: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

UniProt: P17643