Tyrosinase-Related Protein 1 antibody (TRP1)

Catalog No. ABIN5708055

The Rabbit Monoclonal anti-Tyrosinase-Related Protein 1 antibody has been validated for IHC (p). It is suitable to detect Tyrosinase-Related Protein 1 in samples from Human and Mouse.

Quick Overview for Tyrosinase-Related Protein 1 antibody (TRP1) (ABIN5708055)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TYRP1-1564R

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Binding Specificity: TRP1

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Isotype: IgG kappa

Application Details

Application Notes: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.\. Immunohistochemistry (FFPE) : 5-10 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: Tyrosinase-Related Protein-1

Background: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.