IL12RB1 antibody (Internal Region)

Catalog No. ABIN571176

This anti-IL12RB1 antibody is a Goat Polyclonal antibody detecting IL12RB1 in WB and ELISA. Suitable for Human.

Quick Overview for IL12RB1 antibody (Internal Region) (ABIN571176)

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IL12RB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-IL12RB1 Antibody

Binding Specificity: Internal Region

Purpose: IL12RB1

Sequence: HVSVKNHSLD SVS

Specificity: This antibody is expected to recognize isoform 1 (NP_005526.1) only.

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-HVSVKNHSLDSVS, from the internal region of the protein sequence according to NP_005526.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 100 kDa band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 73.1 kDa according to NP_005526.1). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for IL12RB1

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Alternative Name: IL12RB1

Background: IL12RB1, interleukin 12 receptor, beta 1, CD212, IL-12R-BETA1, IL12RB, MGC34454, IL-12 receptor beta component, interleukin-12 receptor beta-1 chain

Gene ID: 3594

NCBI Accession: NP_005526

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation