Cyclin D1 antibody
Quick Overview for Cyclin D1 antibody (ABIN574432)
Target
See all Cyclin D1 (CCND1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Brand
- IHC-plus™
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Specificity
- The antibody CD1.1 recognizes cyclin D1, an ubiquitously expressed 33 kD protein that migrates as a 36 kD band under reducing SDS-PAGE conditions.
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Purification
- Protein A purified
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Immunogen
- Purified cyclin D1 protein.
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Isotype
- IgG1
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Application Notes
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Approved: ELISA, Flo, ICC (1 μg/mL), IHC, IHC-Fr (2 μg/mL), IHC-P (10 μg/mL), IP, WB (1 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Cyclin D1 (CCND1)
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Alternative Name
- CCND1 / Cyclin D1
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Background
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Name/Gene ID: CCND1
Synonyms: CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene -
Gene ID
- 595
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UniProt
- P24385
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Pathways
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
Target
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