XPA antibody (AA 1-273)

Catalog No. ABIN5775933

This Mouse Monoclonal antibody specifically detects XPA in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for XPA antibody (AA 1-273) (ABIN5775933)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT71H3

Product Details anti-XPA Antibody

Binding Specificity: AA 1-273

Purpose: Human XPA antibody

Purification: Purified

Immunogen: Recombinant human XPA (1-273aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Alternative Name: XPA

Background: XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.

NCBI Accession: NP_000371

Pathways: DNA Damage Repair