OTUB1 antibody (AA 1-271)

Catalog No. ABIN5775962

The Mouse Monoclonal anti-OTUB1 antibody (Clone AT17E10) (ABIN5775962) specifically detects OTUB1 in WB, ELISA, ICC and IF. The antibody is reactive with Human samples.

Quick Overview for OTUB1 antibody (AA 1-271) (ABIN5775962)

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OTUB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT17E10

Product Details anti-OTUB1 Antibody

Binding Specificity: AA 1-271

Purpose: Human Otubain-1/OTUB1 antibody

Purification: Purified

Immunogen: Recombinant human OTUB1 (1-271aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for OTUB1

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Alternative Name: Otubain-1/OTUB1

Background: Otubain 1, also known as OTUB1, is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with an ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth.

NCBI Accession: NP_060140