PDHX antibody (AA 54-501)

Catalog No. ABIN5775964

The Mouse Monoclonal anti-PDHX antibody is suitable to detect PDHX in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PDHX antibody (AA 54-501) (ABIN5775964)

Target: PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDHX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: AT1E11

Product Details anti-PDHX Antibody

Binding Specificity: AA 54-501

Purpose: Human PDHX antibody

Purification: Purified

Immunogen: Recombinant human PDHX (54-501aa) purified from E. coli.

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PDHX

Target: PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))

Alternative Name: PDHX

Background: The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit, also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex.

NCBI Accession: NP_003468