NMT1 antibody (AA 1-496)
Quick Overview for NMT1 antibody (AA 1-496) (ABIN5776038)
Target
See all NMT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-496
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Immunogen
- Recombinant human NMT1 (1-496aa) purified from E. coli
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- NMT1 (N-Myristoyltransferase 1 (NMT1))
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Alternative Name
- NMT1
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Background
- Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO. Recombinant human NMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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NCBI Accession
- NP_066565
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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