Glutathione Reductase antibody (AA 43-522)

Catalog No. ABIN5776136

The Mouse Monoclonal anti-Glutathione Reductase antibody (Clone AT11D10) (ABIN5776136) specifically detects Glutathione Reductase in WB, ELISA, IF, ICC and FACS. The antibody is reactive with Human samples.

Quick Overview for Glutathione Reductase antibody (AA 43-522) (ABIN5776136)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT11D10

Product Details anti-Glutathione Reductase Antibody

Binding Specificity: AA 43-522

Purpose: Human Glutathione Reductase/GSR antibody

Immunogen: Recombinant human GSR (43-522aa) purified from E.coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: Glutathione Reductase/GSR

Background: Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase catalyzes the reduction of glutathione disulfide (GSSG) to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell. Glutathione reductase functions as dimeric disulfide oxidoreductase and utilizes an FAD prosthetic group and NADPH to reduce one mole of GSSG to two moles of GSH.

NCBI Accession: NP_000628

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis