TP53I3 antibody (AA 1-332)

Catalog No. ABIN5776206

This Mouse Monoclonal antibody specifically detects TP53I3 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for TP53I3 antibody (AA 1-332) (ABIN5776206)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TP53I3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1C9

Product Details anti-TP53I3 Antibody

Binding Specificity: AA 1-332

Purpose: Human PIG3/TP53I3 antibody

Purification: Purified

Immunogen: Recombinant human TP53I3 (1-332aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Alternative Name: PIG3/TP53I3

Background: TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1, 2-naphtoquinone over 1, 4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.

NCBI Accession: NP_671713

Pathways: p53 Signaling