CD46 antibody (AA 35-313)

Catalog No. ABIN5776214

This anti-CD46 antibody is a Mouse Monoclonal antibody detecting CD46 in WB, FACS, ELISA, IHC, IF and ICC. Suitable for Human.

Quick Overview for CD46 antibody (AA 35-313) (ABIN5776214)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT2G9

Product Details anti-CD46 Antibody

Binding Specificity: AA 35-313

Immunogen: Recombinant human CD46 (35-313aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background: Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

NCBI Accession: NP_758860

Pathways: Regulation of Actin Filament Polymerization