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CHEK2 antibody (pSer516)

This Rabbit Polyclonal antibody specifically detects CHEK2 in WB. It exhibits reactivity toward Human, Monkey, Dog, Cow, Rabbit and Horse.
Catalog No. ABIN594244

Quick Overview for CHEK2 antibody (pSer516) (ABIN594244)

Target

See all CHEK2 Antibodies
CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity

  • 238
  • 86
  • 72
  • 16
  • 12
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Human, Monkey, Dog, Cow, Rabbit, Horse

Host

  • 219
  • 22
  • 1
Rabbit

Clonality

  • 207
  • 35
Polyclonal

Conjugate

  • 113
  • 11
  • 9
  • 9
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
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  • 7
  • 7
  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This CHEK2 antibody is un-conjugated

Application

  • 203
  • 79
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  • 71
  • 44
  • 39
  • 34
  • 28
  • 24
  • 21
  • 18
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 25
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    • 19
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    • 16
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    • 15
    • 9
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    • 8
    • 8
    • 6
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    pSer516

    Specificity

    Recognizes human Chk2 when phosphorylated at serine 516.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic phosphopeptide corresponding to human Chk2 around the phosphorylation site of serine 516 (Q-P-SP-T-S).

    Type of Immunogen: Synthetic phospho-peptide

    Isotype

    IgG
  • Application Notes

    Approved: WB (1:500 - 1:1000)

    Usage: Suitable for use in Western blot:1:500-1:1000.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Aliquot to Avoid repeated freezing and thawing.

    Storage

    4 °C,-20 °C

    Storage Comment

    May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
  • Target

    CHEK2 (Checkpoint Kinase 2 (CHEK2))

    Alternative Name

    CHEK2 / CHK2

    Background

    Name/Gene ID: CHEK2
    Subfamily: CDS1
    Family: Protein Kinase

    Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425

    Gene ID

    11200

    UniProt

    O96017

    Pathways

    p53 Signaling, Apoptosis, Cell Division Cycle
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