SHC1 antibody

Catalog No. ABIN597688

This Rabbit Polyclonal antibody specifically detects SHC1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig and Monkey.

Quick Overview for SHC1 antibody (ABIN597688)

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHC1 Antibody

Specificity: Recognizes human Shc1. Species cross-Reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human Shc1 around the phosphorylation site of tyrosine 349 (H-Q-YP-Y-N).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:500 - 1:1000)

Usage: Suitable for use in Western blot:1:500-1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for SHC1

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Alternative Name: p66 / SHC

Background: Name/Gene ID: SHC1

Synonyms: SHC1, p46 shc, p52 shc, SH2 domain protein C1, p66, SHCA, SHC, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A

Gene ID: 6464

UniProt: P29353

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2