BIM antibody

Catalog No. ABIN600512

The Rabbit Polyclonal anti-BIM antibody has been validated for WB and IHC. It is suitable to detect BIM in samples from Human, Mouse, Rat, Monkey, Dog and Horse.

Quick Overview for BIM antibody (ABIN600512)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human, Mouse, Rat, Monkey, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BIM Antibody

Specificity: Recognizes mouse Bim. Species cross-Reactivity: human, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic non-phosphopeptide corresponding to mouse BIM around the phosphorylation site of serine 65 (P-A-SP-P-G).

Type of Immunogen: Synthetic Non-phosphopeptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BCL2L11 / BIM

Background: Name/Gene ID: BCL2L11
Family: Apoptosis

Synonyms: BCL2L11, BIM-alpha6, BIM-beta7, Bcl-2-like protein 11, BIM-beta6, BimL, BimS, Bcl-2 interacting protein Bim, BimEL, BAM, Bcl2-L-11, BIM, BOD

Gene ID: 10018

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity