CHEK2 antibody (pThr387)
Quick Overview for CHEK2 antibody (pThr387) (ABIN601012)
Target
See all CHEK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- pThr387
-
Specificity
- Recognizes human Chk2 when phosphorylated at Thr387. Species cross-Reactivity: mouse, rat.
-
Purification
- Immunoaffinity purified
-
Immunogen
-
Synthetic phosphopeptide corresponding to human CHK2 around the phosphorylation site of threonine 387 (C-G-TP-P-T).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
-
-
-
-
Application Notes
-
Approved: ELISA (1:4000), IHC (1:50 - 1:100), WB (1:500 - 1:1000)
Usage: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. ELISA:1:4000. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100. -
Comment
-
Target Species of Antibody: Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Aliquot to Avoid repeated freezing and thawing.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
-
-
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
-
Alternative Name
- CHEK2 / CHK2
-
Background
-
Name/Gene ID: CHEK2
Subfamily: CDS1
Family: Protein Kinase
Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425 -
Gene ID
- 11200
-
UniProt
- O96017
-
Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
Target
-