GRIN1/NMDAR1 antibody (pSer897)

Catalog No. ABIN602062

This Rabbit Polyclonal antibody specifically detects GRIN1/NMDAR1 in WB, IHC and IP. It exhibits reactivity toward Rat.

Quick Overview for GRIN1/NMDAR1 antibody (pSer897) (ABIN602062)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-GRIN1/NMDAR1 Antibody

Binding Specificity: pSer897

Specificity: Recognizes rat NR1 when phosphorylated at Ser897 at ~120kD. Species sequence Homology (100 % ): Mouse, human.

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to rat NR1 phosphorylated at Ser897 (KLH).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50), IP, WB (1 μg/mL)

Usage: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Western Blot: 1 μg/mL detected NR1 in 10 μg of rat brain microsomal tissue lysate. Immunohistochemistry: 1:50 detected NR1 in normal rat hippocampus. Immunoprecipitation: 10 μg from a previous lot precipitated NR1 from rat brain microsomal RIPA lysate.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 150 mM sodium chloride, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: GRIN1 / NMDAR1

Background: Name/Gene ID: GRIN1
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1

Gene ID: 2902

UniProt: Q05586

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity