Tuberin antibody (pSer939)

Catalog No. ABIN602468

The Rabbit Polyclonal anti-Tuberin antibody has been validated for ELISA, WB and IHC. It is suitable to detect Tuberin in samples from Human, Mouse, Rat, Monkey, Rabbit, Cow, Horse and Dog.

Quick Overview for Tuberin antibody (pSer939) (ABIN602468)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Cow, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Tuberin Antibody

Binding Specificity: pSer939

Specificity: Recognizes human TSC2, phosphorylated at (Ser939). Species cross-Reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human Tsc2 around the phosphorylation site of serine 939 (S-T-SP-L-N).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:4000), IHC (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. ELISA:1:4000. Western Blot:1:500-1:1000. Immunohistochemistry:1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: Tuberin / TSC2

Background: Name/Gene ID: TSC2

Synonyms: TSC2, LAM, Tuberous sclerosis 2 protein, TSC4, Tuberin, Tuberous sclerosis 2

Gene ID: 7249

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus