ITGA4 antibody (Biotin)
Quick Overview for ITGA4 antibody (Biotin) (ABIN610119)
Target
See all ITGA4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- CD49d molecule of about 145 kd.
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Purification
- Protein A purified
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Immunogen
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Human peripheral myeloma cells.
Type of Immunogen: Cells -
Isotype
- IgG1
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Application Notes
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Approved: Flo, Func, IHC
Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C. Do not freeze.
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Identification of LIL-STAT in monocytic leukemia cells and monocytes after stimulation with interleukin-6 or interferon gamma." in: Blood, Vol. 98, Issue 13, pp. 3849-52, (2001) (PubMed).
: "Interleukin-4 mediates cell growth inhibition through activation of Stat1." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10212-7, (2000) (PubMed).
: "Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter." in: Cell, Vol. 74, Issue 6, pp. 1135-45, (1993) (PubMed).
: "
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Identification of LIL-STAT in monocytic leukemia cells and monocytes after stimulation with interleukin-6 or interferon gamma." in: Blood, Vol. 98, Issue 13, pp. 3849-52, (2001) (PubMed).
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- ITGA4 (Integrin alpha 4 (ITGA4))
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Alternative Name
- ITGA4 / VLA-4 / CD49d
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Background
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Name/Gene ID: ITGA4
Family: Integrin
Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen -
Gene ID
- 3676
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UniProt
- P13612
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Pathways
- Integrin Complex
Target
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