ITGA4 antibody

Catalog No. ABIN610122

This anti-ITGA4 antibody is a Mouse Monoclonal antibody detecting ITGA4 in FACS, IHC and Func. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for ITGA4 antibody (ABIN610122)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: BU49

Product Details anti-ITGA4 Antibody

Specificity: CD49d molecule of about 145 kd.

Purification: Protein A purified

Immunogen: Human peripheral myeloma cells.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, IHC

Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-ITGA4 antibody (ABIN610122)

Aplin, Stewart, Assoian, Juliano: "Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 273-82, (2001) (PubMed).

Short, Boyer, Juliano: "Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12970-7, (2000) (PubMed).

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: ITGA4 / VLA-4 / CD49d

Background: Name/Gene ID: ITGA4
Family: Integrin

Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen

Gene ID: 3676

UniProt: P13612

Pathways: Integrin Complex