p53 antibody (FITC)

Catalog No. ABIN610211

The Mouse Monoclonal anti-p53 antibody has been validated for WB, IHC and FACS. It is suitable to detect p53 in samples from Human, Mouse, Rat, Cow, Hamster and Chicken. There are 2+ publications available.

Quick Overview for p53 antibody (FITC) (ABIN610211)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human, Mouse, Rat, Cow, Hamster, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This p53 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PAb240

Product Details anti-p53 Antibody (FITC)

Specificity: Denaturization resistant p53 epitope between amino acids 156-214. It is cross reactive with human, mouse, hamster, rat, bovine and chicken tissues.

Purification: Protein A purified

Immunogen: Murine p53 fragment expressed in E. coli.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, IHC, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

References for anti-p53 antibody (FITC) (ABIN610211)

Tomicic, Thust, Kaina: "Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation." in: Oncogene, Vol. 21, Issue 14, pp. 2141-53, (2002) (PubMed).

Jiang, Clark: "Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 6025-33, (2001) (PubMed).

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: TP53 / p53

Background: Name/Gene ID: TP53
Family: P53

Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

Gene ID: 7157

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect