Endoglin antibody (PE)

Catalog No. ABIN610352

The Mouse Monoclonal anti-Endoglin antibody has been validated for FACS, IHC and Func. It is suitable to detect Endoglin in samples from Human. There are 2+ publications available.

Quick Overview for Endoglin antibody (PE) (ABIN610352)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Clone: SN6-N1-3A1

Product Details anti-Endoglin Antibody (PE)

Specificity: CD105 homodimer with a molecular weight of about 160 kd.

Purification: Gel filtration

Immunogen: Membrane preparation of human B-lineage leukemia cells.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, Func, IHC

Usage: Function: Augments binding of TGF-b1 to CD105 expressing leukemia cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

References for anti-Endoglin antibody (PE) (ABIN610352)

Taupin, Tian, Kedersha, Robertson, Anderson: "The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1629-33, (1995) (PubMed).

Kawakami, Tian, Duan, Streuli, Schlossman, Anderson: "Identification and functional characterization of a TIA-1-related nucleolysin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8681-5, (1992) (PubMed).

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background: Name/Gene ID: ENG

Synonyms: ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin

Gene ID: 2022

UniProt: P17813