ADAM22 antibody (AA 223-400)

Catalog No. ABIN6136529

This Rabbit Polyclonal antibody specifically detects ADAM22 in WB. It exhibits reactivity toward Human.

Quick Overview for ADAM22 antibody (AA 223-400) (ABIN6136529)

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM22 Antibody

Binding Specificity: AA 223-400

Sequence: SKRQLRRYPR NVEEETKYIE LMIVNDHLMF KKHRLSVVHT NTYAKSVVNM ADLIYKDQLK TRIVLVAMET WATDNKFAIS ENPLITLREF MKYRRDFIKE KSDAVHLFSG SQFESSRSGA AYIGGICSLL KGGGVNEFGK TDLMAVTLAQ SLAHNIGIIS DKRKLASGEC KCEDTWSG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 of human ADAM22 (NP_004185.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM22

Target: ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))

Alternative Name: ADAM22

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.,ADAM22,ADAM 22,MDC2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM22

Molecular Weight: 91 kDa/95 kDa/96 kDa/100 kDa

Gene ID: 53616

UniProt: Q9P0K1