ADCY2 antibody (AA 430-600)

Catalog No. ABIN6136559

The Rabbit Polyclonal anti-ADCY2 antibody (ABIN6136559) specifically detects ADCY2 in WB. The antibody is reactive with Human samples.

Quick Overview for ADCY2 antibody (AA 430-600) (ABIN6136559)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADCY2 Antibody

Binding Specificity: AA 430-600

Sequence: VTLEHLNGAY KVEEGDGDIR DPYLKQHLVK TYFVINPKGE RRSPQHLFRP RHTLDGAKMR ASVRMTRYLE SWGAAKPFAH LHHRDSMTTE NGKISTTDVP MGQHNFQNRT LRTKSQKKRF EEELNERMIQ AIDGINAQKQ WLKSEDIQRI SLLFYNKVLE KEYRATALPA F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-600 of human ADCY2 (NP_065433.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: ADCY2

Background: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.,ADCY2,AC2,HBAC2,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,ADCY2

Molecular Weight: 103 kDa/123 kDa

Gene ID: 108

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma