ALDH7A1 antibody (AA 430-539)

Catalog No. ABIN6136782

This Rabbit Polyclonal antibody specifically detects ALDH7A1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ALDH7A1 antibody (AA 430-539) (ABIN6136782)

Target: ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH7A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ALDH7A1 Antibody

Binding Specificity: AA 430-539

Sequence: APILYVFKFK NEEEVFAWNN EVKQGLSSSI FTKDLGRIFR WLGPKGSDCG IVNVNIPTSG AEIGGAFGGE KHTGGGRESG SDAWKQYMRR STCTINYSKD LPLAQGIKFQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-539 of human ALDH7A1 (NP_001173.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH7A1

Target: ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))

Alternative Name: ALDH7A1

Background: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.,ALDH7A1,ATQ1,EPD,PDE,ALDH7A1

Molecular Weight: 51 kDa/55 kDa/58 kDa

Gene ID: 501

UniProt: P49419

Pathways: Sensory Perception of Sound