ATP1B2 antibody (AA 68-290)

Catalog No. ABIN6137310

This Rabbit Polyclonal antibody specifically detects ATP1B2 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for ATP1B2 antibody (AA 68-290) (ABIN6137310)

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ATP1B2 Antibody

Binding Specificity: AA 68-290

Sequence: DHTPKYQDRL ATPGLMIRPK TENLDVIVNV SDTESWDQHV QKLNKFLEPY NDSIQAQKND VCRPGRYYEQ PDNGVLNYPK RACQFNRTQL GNCSGIGDST HYGYSTGQPC VFIKMNRVIN FYAGANQSMN VTCAGKRDED AENLGNFVMF PANGNIDLMY FPYYGKKFHV NYTQPLVAVK FLNVTPNVEV NVECRINAAN IATDDERDKF AGRVAFKLRI NKT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-290 of human ATP1B2 (NP_001669.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP1B2

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Alternative Name: ATP1B2

Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. Two transcript variants encoding different isoforms have been found for this gene.,ATP1B2,AMOG,Signal Transduction,Endocrine & Metabolism,ATP1B2

Molecular Weight: 33 kDa

Gene ID: 482

UniProt: P14415

Pathways: Thyroid Hormone Synthesis