ATP1B2 antibody (AA 115-141)

Catalog No. ABIN653219

The Rabbit Polyclonal anti-ATP1B2 antibody is suitable to detect ATP1B2 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for ATP1B2 antibody (AA 115-141) (ABIN653219)

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB22612

Product Details anti-ATP1B2 Antibody

Binding Specificity: AA 115-141

Predicted Reactivity: B, M, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP1B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-141 amino acids from the Central region of human ATP1B2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ATP1B2

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Alternative Name: ATP1B2

Background: The protein belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

Molecular Weight: 33367

Gene ID: 482

NCBI Accession: NP_001669

UniProt: P14415

Pathways: Thyroid Hormone Synthesis